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Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://www.parapathology.com/systemic-pathology/neuropathology/injury-in-central-nervous-system-and-cerebrovascular-diseases.md). # Injury in central nervous system and cerebrovascular diseases ## Injury in central nervous system and cerebrovascular diseases ## Injury in central nervous system and cerebrovascular diseases Name of the Lecture: Injury in central nervous system and cerebrovascular diseases Required Prior Knowledge: * Basic vascular anatomy of CNS * Basic gross anatomy of cerebral hemispheres and cerebellum * Basic histology of cell types in CNS * Basic physiology of cerebrospinal fluid * Basic physiology of blood brain barrier Aim of the Lecture: * To teach basic injury response of CNS to various lesions * To teach pathology of fluid flows in CNS and pathologies related to vascular lesions Goals of the lecture: The students will learn: * The basic reaction patterns to injury in CNS and how it differs from those of other organ systems * Fluid imbalances in CNS * Pathologies of flow of cerebrospinal fluid * Cerebrovascular diseases * The pathogenetic mechanisms of these diseases, their macroscopic and microscopic features The students will compare the morpgologic and pathophysiologic features with clinical presentations. Lecture Outlines: * Patterns of injury in the nervous system * * Neuronal Injury, Red Neurons * Astrocytic reaction to the injury, Gliosis * Edema * * Vasogenic Edema * Cytotoxic Edema * Herniation * * Subfalcine (cingulate) herniation * Transtentorial (uncinate) herniation * Tonsillar herniation * Hydrocephalus * * Noncommunicating hydrocephalus * Communicating hydrocephalus * Cerebrovascular Diseases * * Stroke * Hypoxia * Global Ischemia * Focal Ischemia * Nonhemorrhagic Infarcts * Hemorrhagic Infarcts * Intracranial Hemorrhage * Cerebral Amyloid Angiopathy * Saccular Aneurysms * Vascular Malformations * Hypertensive Cerebrovascular Diseases * Vasculitis References: Robbins Basic Pathology, 9th edition, pp: 811, 812-813, 814-819 Name of the Lecture: Injury in central nervous system and cerebrovascular diseases Required Prior Knowledge: * Basic vascular anatomy of CNS * Basic gross anatomy of cerebral hemispheres and cerebellum * Basic histology of cell types in CNS * Basic physiology of cerebrospinal fluid * Basic physiology of blood brain barrier Aim of the Lecture: * To teach basic injury response of CNS to various lesions * To teach pathology of fluid flows in CNS and pathologies related to vascular lesions Goals of the lecture: The students will learn: * The basic reaction patterns to injury in CNS and how it differs from those of other organ systems * Fluid imbalances in CNS * Pathologies of flow of cerebrospinal fluid * Cerebrovascular diseases * The pathogenetic mechanisms of these diseases, their macroscopic and microscopic features The students will compare the morpgologic and pathophysiologic features with clinical presentations. Lecture Outlines: * Patterns of injury in the nervous system * * Neuronal Injury, Red Neurons * Astrocytic reaction to the injury, Gliosis * Edema * * Vasogenic Edema * Cytotoxic Edema * Herniation * * Subfalcine (cingulate) herniation * Transtentorial (uncinate) herniation * Tonsillar herniation * Hydrocephalus * * Noncommunicating hydrocephalus * Communicating hydrocephalus * Cerebrovascular Diseases * * Stroke * Hypoxia * Global Ischemia * Focal Ischemia * Nonhemorrhagic Infarcts * Hemorrhagic Infarcts * Intracranial Hemorrhage * Cerebral Amyloid Angiopathy * Saccular Aneurysms * Vascular Malformations * Hypertensive Cerebrovascular Diseases * Vasculitis References: Robbins Basic Pathology, 9th edition, pp: 811, 812-813, 814-819 Name of the Lecture: Injury in central nervous system and cerebrovascular diseases Required Prior Knowledge: * Basic vascular anatomy of CNS * Basic gross anatomy of cerebral hemispheres and cerebellum * Basic histology of cell types in CNS * Basic physiology of cerebrospinal fluid * Basic physiology of blood brain barrier Aim of the Lecture: * To teach basic injury response of CNS to various lesions * To teach pathology of fluid flows in CNS and pathologies related to vascular lesions Goals of the lecture: The students will learn: * The basic reaction patterns to injury in CNS and how it differs from those of other organ systems * Fluid imbalances in CNS * Pathologies of flow of cerebrospinal fluid * Cerebrovascular diseases * The pathogenetic mechanisms of these diseases, their macroscopic and microscopic features The students will compare the morpgologic and pathophysiologic features with clinical presentations. Lecture Outlines: * Patterns of injury in the nervous system * * Neuronal Injury, Red Neurons * Astrocytic reaction to the injury, Gliosis * Edema * * Vasogenic Edema * Cytotoxic Edema * Herniation * * Subfalcine (cingulate) herniation * Transtentorial (uncinate) herniation * Tonsillar herniation * Hydrocephalus * * Noncommunicating hydrocephalus * Communicating hydrocephalus * Cerebrovascular Diseases * * Stroke * Hypoxia * Global Ischemia * Focal Ischemia * Nonhemorrhagic Infarcts * Hemorrhagic Infarcts * Intracranial Hemorrhage * Cerebral Amyloid Angiopathy * Saccular Aneurysms * Vascular Malformations * Hypertensive Cerebrovascular Diseases * Vasculitis References: Robbins Basic Pathology, 9th edition, pp: 811, 812-813, 814-819